Rare Events, Transition Pathways and Reaction Rates |

Introduction |
Zero-Temperature String Method |
Finite-Temperature String Method |
Modified String Method |
Reference |

## Algorithm |
## Download Code |

A major problem with the available algorithms to study rare
events is slow convergence. Since the original and simplified string methods rely heavily on steepest
descent minimization schemes, the convergence is exponential. This can become decisive when the
system size is very large.
In order to overcome this problem, we propose an algorithm which borrows some ideas from String
method and Locally Updated Planes (LUP) method proposed by Elber and co-workers :
Reaction path study of conformational
transitions and helix formation in a tetrapeptide
The central idea is to start with a guess path (say N intermediate images) between the initial
and final states. At each image ( |