CB lesion in development
Xander: what about other brain regions?

sensitive periods (different in neocortex)

but CB effects are inverse!

cerebellar mutism can last weeks to 2 years (tens of months) - in that case to par

is the necessary information specific? i.e. is the need generic or is information conveyed?

visual information: provides information that drives refinement

sensitive period for language: think of second language acquisitioin sensitive period, age 8

when does movement mature?

CB projections to red nucleus are pruned - or change - after age 2

Neurodevelopmental disorders: CB and schizophrenia, dyslexia?

CB is necessary for normal development and refinement of other brain regions

1) abilities come on line; timeline of refinement or acquisition
2) whenever neocortex is involved, CB lesion during that time messes up the capacity
	QUESTIONS: is CB there? are tracts there? is NEO there? and...is it sensitive?

back to other regions. early hippocampal damage leads to later neocortical deficits

WHAT ABOUT localization within CB?

Amaral thinks posterior CB is involved in a bunch of neurodevelopmental disorders
	vermis: projects to saccadic eye movements
	posterior: Strick traces these to PFC; superior vs. inferior
		anterior is smaller, lobule 8 9 10 flocculus

posterior: lateralization of language, converse to neocortex. in adults

primary sensory sensitive periods: might not expect them to be CB-sensitive
	what about auditory acuity?

where does face recognition fall into this?

why is CB needed? trophic support vs. specific information.

Rutter orphanage kids: at what age do they go in? are they selected for?

EXPERIMENTS ONE COULD DO:
analogous experiment to HubelWiesel:
	first identify something one could study in animals
		need a developmental map for that
	inactivate CB temporarily, then let it come back: does the sensitive period lengthen?
	
is bad CB input worse than no CB input?

lesion at different ages, see what neocortical patterns are

lesion CB, see if neocortical LTP/LTD are there for longer. could be a bad experiment

doxycycline experiment

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1) Sensitive periods for NEO function (identify more of them)
2) Age-dependent CB effects (identify more of them)
3) Roles of CB: trophic vs. specific (probably can't distinguish? maybe not so important)
4) CB role: error detector? so like H&W visual experiments
5) Experiments one could do

carl fristen - NEO as error detector

scholar.google.com search: cerebellum damage "bayley scales" OR "mccarthy scales" OR "kaufman assessment" very useful!